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Direktoratet for medisinske produkter (tidligere Statens legemiddelverk) har ansvaret for bytteordningen, og har konkretisert vilkårene for hva som regnes for tungtveiende medisinske grunner for et medisinbytte. Forsiktighetsregler Bilkjøring Zopiklon kan påvirke kjøreevnen dersom det tas mindre enn tolv timer før kjøring, hvis de tas i stø